Roughly 110 miles from Anchorage and 150 from the entrance of Denali National Park, Talkeetna is a favorite middle-point for visitors traveling between those two Alaska destinations. The small town sits at the confluence of the Susitna, Talkeetna, and Chulitna rivers. It is located at the end of the Talkeetna Spur, a 15-mile side road off the Parks Highway.
With North America's tallest mountain a mere 40 miles northwest, Talkeetna is a popular jumping off point for Denali flightseeing tours. The local airport is about a half a mile from the town center. Many local restaurants, galleries, and shops are on Talkeetna's Main Street, which runs for just a few blocks from Nagley's Store to the Susitna riverfront.
Talkeetna is on the Alaska Railroad's Denali Star route. The train depot is just over half a mile from Main Street. Looking farther afield, Talkeetna is 60 miles from Byers Lake, a tranquil kayaking destination within Denali State Park, and about 270 miles from Fairbanks